“It's hard to tell where narcolepsy ends and where I begin.”– Nicki
THE KNOW NARCOLEPSY SURVEY
Results from the national Know Narcolepsy Survey of 1654 US adults, including people living with narcolepsy (n=200), the general public (n=1203), and physicians who have treated patients with narcolepsy in the last 2 years (n=251), underscore that narcolepsy can be a substantial and continuing burden. Narcolepsy can have an impact on a person’s daily functioning and social well-being. Of the people living with narcolepsy surveyed, 68% (n=135) agreed they never feel like a “normal” person, and only 12% (n=24) agreed their symptoms are completely or mostly under control.14
Significant Comorbidities Exist in Narcolepsy
People with narcolepsy have a higher prevalence of comorbidities compared with the average adult.2 Psychiatric comorbidities, especially depression, are reported up to 4 times more often in people with narcolepsy,1 and the risk for cardiovascular diseases is higher.2
Comorbidities in people living with narcolepsy
Stories from people living with narcolepsy can help you understand the impact of the disorder.
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- American Academy of Sleep Medicine. International Classification of Sleep Disorders. 3rd ed. Darien, IL: American Academy of Sleep Medicine; 2014.
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- Kapella MC, Berger BE, Vern BA, Vispute S, Prasad B, Carley DW. Health-related stigma as a determinant of functioning in young adults with narcolepsy. PLoS One. 2015;10(4):1-12.
- Ohayon MM. Narcolepsy is complicated by high medical and psychiatric comorbidities: a comparison with the general population. Sleep Med. 2013;14(6):488-492.
- Filardi M, Pizza F, Tonetti L, Antelmi E, Natale V, Plazzi G. Attention impairments and ADHD symptoms in adult narcoleptic patients with and without hypocretin deficiency. PLoS One. 2017;12(8):1-12.
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- Ahmed I, Thorpy M. Clinical features, diagnosis and treatment of narcolepsy. Clin Chest Med. 2010;31(2):371-381.
- Overeem S, van Nues S, van der Zande WL, Donjacour CE, van Mierlo P, Lammers GJ. The clinical features of cataplexy: a questionnaire study in narcolepsy patients with and without hypocretin-1 deficiency. Sleep Med. 2011;12(1):12-18.
- Ahmed IM, Thorpy MJ. Clinical evaluation of the patient with excessive sleepiness. In: Thorpy MJ, Billiard M, eds. Sleepiness: Causes, Consequences and Treatment. Cambridge, UK: Cambridge University Press; 2011:36-47.
- Data on file. Harmony Biosciences. 2018.
- Kok SW, Overeem S, Visscher TLS, et al. Hypocretin deficiency in narcoleptic humans is associated with abdominal obesity. Obes Res. 2003;11(9):1147-1154.