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Narcolepsy Resources for Healthcare Professionals
Access tools and downloadable resources for you and your office.
Narcolepsy Resources and Tools
A Quick Guide for Evaluating the Impact of Narcolepsy
Understanding the impact of excessive daytime sleepiness and other symptoms on patient functioning and quality of life is important for improving clinical outcomes.
A Quick Guide for Evaluating the Impact of Narcolepsy
Clinical Conversation Simulator Tool
Use this tool to practice your clinical interview skills and get insights from the experts on evaluating the impact of ongoing symptoms in people living with narcolepsy.
Clinical Conversation Simulator Tool
Narcolepsy Assessment Tool
Use this tool to help your patients assess how narcolepsy may be interfering with their lives. Encourage them to share their results at their next appointment.
Narcolepsy Assessment Tool
A Guide to the Pathophysiology of Narcolepsy
A concise guide to understanding signs and symptoms that reflect sleep-wake state instability as well as the underlying neuronal processes behind stable wakefulness.
A Guide to the Pathophysiology of Narcolepsy
Epworth Sleepiness Scale (ESS)
An 8-item questionnaire to assess daytime sleepiness based on a person’s sleep propensity in common situations.
Access scale »Narcolepsy Severity Scale (NSS)
A 15-item scale that evaluates the frequency and impact of the five main narcolepsy symptoms.
Access scale »Functional Outcomes of Sleep Questionnaire-10 (FOSQ-10)
A 10-item questionnaire that assesses the impact of excessive daytime sleepiness on daily activities.
Access scale »Publications
Carrie E Mahoney, Andrew Cogswell, Igor J Koralnik, Thomas E Scammell
This review discusses the current understanding of how hypocretin neurons regulate sleep-wake behavior and the consequences of the loss of hypocretin neurons. It also summarizes the developing evidence that narcolepsy is an autoimmune disorder that may be caused by a T cell–mediated attack on the hypocretin neurons.
Adrienne Elisabeth van der Hoeven, Rolf Fronczek, Mink Sebastian Schinkelshoek, Frederik Willem Cornelis Roelandse, Jaap Adriaan Bakker, Sebastiaan Overeem, Denise Bijlenga, Gert Jan Lammers
Individuals with intermediate hypocretin-1 levels or typical cataplexy more often have outcomes fitting the PSG and MSLT criteria for narcolepsy than those with normal levels or atypical cataplexy. In addition, typical cataplexy has a much stronger association with hypocretin-1 deficiency than atypical cataplexy. The findings from this study helped inform the updates made to the International Classification of Sleep Disorders, 3rd ed. Text Revision (ICSD-3-TR) guidelines in 2023.
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